Severe Acute Respiratory Archives

L452R and Y453F SARS-CoV-2 mutations increase transmission and evade immunity

04/12/2021 ACE2, Antigen, binding affinity, blood, coronavirus, Coronavirus Disease COVID-19, Human Leukocyte Antigen, Immune Response, Leukocyte, Mutation, protein, Protein Stability, Public Health, Receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome

Mutations from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have created multiple variants. Some variants, such as those found

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New nanoparticle SARS-CoV-2 vaccine confers robust protection with single dose after two weeks

04/06/2021 ACE2, Angiotensin, antibodies, antibody, Antigen, Cell, coronavirus, Coronavirus Disease COVID-19, Glycine, Glycoprotein, Heparin, Immune Response, immunization, Nanoparticle, Nanoparticles, protein, Receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome, vaccine, virus

In a methodologically ‘state-of-the-art’ approach, US researchers have developed a protein-based nanoparticle vaccine against coronavirus disease (COVID-19), with a swift

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Risk of SARS-CoV-2 from reinfected individuals with previous infection or vaccination

04/03/2021 antibody, coronavirus, Coronavirus Disease COVID-19, efficacy, Mortality, pandemic, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, vaccine

A technical report recently published by the European Center for Disease Prevention and Control (ECDC) has summarized all available literature

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Quantum dot-based affinity biosensors in microfluidic systems offer an alternative SARS-CoV-2 diagnostics platform

03/17/2021 Analyte, antibodies, Biosensor, Cell, Cell Imaging, coronavirus, Coronavirus Disease COVID-19, Diagnostics, Fluorescence, FRET, Imaging, protein, Quantum Dots, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, virus

In a new study published in Emergent Materials, researchers show how microfluidic systems integrated with quantum dot-based affinity biosensors can

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Research looks at inflammatory nature of lipid nanoparticle component in mRNA vaccines

03/15/2021 antibodies, Cell, Chemokines, coronavirus, Cytokines, fever, Immune Response, inflammation, Intracellular, Lipids, Macrophage, Nanoparticle, Nanoparticles, Necroptosis, Nucleoside, Pain, peptides, Preclinical, protein, research, respiratory, RNA, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, vaccine

Lipid nanoparticles (LNPs) are the carrier vehicles that protect messenger RNA (mRNA) molecules from degradation and aid intracellular delivery and

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Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19

03/15/2021 antibodies, antibody, assay, Cell, coronavirus, Coronavirus Disease COVID-19, Disability, efficacy, Enzyme, Glycoprotein, immune system, Immunodeficiency, in vitro, in vivo, Mortality, Mutation, pandemic, Receptor, research, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, vaccine, virus

A recent study, currently available on the bioRxiv* preprint server, indicates that a pair of dual-action monoclonal antibodies derived from

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Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

03/09/2021 Antigen, Cell, Chromatography, coronavirus, Coronavirus Disease COVID-19, efficacy, healthcare, Helicobacter pylori, Nanoparticle, Nanoparticles, pandemic, protein, Receptor, respiratory, RNA, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, vaccine, virus, Weight Loss

COVID-19 (coronavirus disease 2019) is caused by a new positive-strand RNA coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),

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Novavax COVID-19 vaccine shows efficacy against South African SARS-CoV-2 variant

03/05/2021 coronavirus, Coronavirus Disease COVID-19, efficacy, HIV, pandemic, Placebo, respiratory, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, syndrome, vaccine, virus

Researchers in the United States and South Africa report that the NVX-CoV2373 vaccine from Novavax has proved effective at preventing

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Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

03/04/2021 ACE2, Angiotensin, Angiotensin-Converting Enzyme 2, Cell, Cell Line, coronavirus, Coronavirus Disease COVID-19, Cytokines, efficacy, Enzyme, fever, genome, in vitro, Influenza, molecule, pandemic, protein, remdesivir, respiratory, RNA, SARS, SARS-CoV-2, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Spike Protein, syndrome, virus

Researchers found a small molecule that inhibits different virus proteins and significantly reduces infection in cells. Combined with the antiviral

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Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

02/25/2021 ACE2, Adenovirus, Angiotensin, Angiotensin-Converting Enzyme 2, blood, Cell, Cell Membrane, coronavirus, Cytotoxicity, Drugs, Enzyme, gene, Genes, genetic, Genetic Information, Induced Pluripotent Stem Cells, Phenotype, protein, Receptor, remdesivir, respiratory, RNA, SARS, SARS-CoV-2, Serine, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Stem Cells, syndrome, virus

The clinical phenotype of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is remarkable

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