Taking Aspirin to protect against colorectal cancer
The use of Aspirin is reduced, even in individuals with a high genetic risk, the probability of colon cancer by about half, so the results of a recent study. May Aspirin is for the prevention of colon cancer use.
In the case of a major international investigation with the participation of researchers from the University of Jyväskylä, it was found that Aspirin seems to protect against bowel cancer, even if genetically there is contingent risk. The results of the current study have been published in the English journal “The Lancet”.
Other studies showed similar results
The findings of the new study is similar to what has been observed in a number of large cardiovascular studies already. Tens of thousands of people were in placebo-controlled trials of Aspirin to cardiovascular events to prevent. In the case of the analysis of the data showed that Aspirin engaging affected people are significantly less likely to have colorectal cancer than those who received only a Placebo.
A new study looked at people with Lynch syndrome
The Participants of the current study have been previously identified as a carrier of Lynch syndrome. The Lynch syndrome due to an increased risk for several types of cancer. Affected individuals carry a Gene which causes an error in the so-called DNA Mismatch repair. The Lynch syndrome is the most common predisposition for cancer, its prevalence lies in the General population overall, in the case of a disease per 250 people. The most Affected are the possible genetic predispositions not aware of reports of the Frog.
What can refer to the Lynch syndrome?
The Lynch syndrome Gene, because of often leads to cancer at a young age, most commonly in the intestines, uterus, bladder, ureters, or bile. Genetic testing is advantageous for Monitoring and targeted prevention of high-risk persons. If in the family, in relatively young age (50-60 years) and is a multiple cancer has occurred, or that some of the members of diseases and different cancer types, in the above-mentioned institutions had should family members of a genetic examination and advice, recommend the researchers.
Aspirin colon cancer risk halved
The long-term results of the current study show that the intake can reduce by 600 mg of Aspirin daily, the risk of colon cancer by half, compared with people who only took a Placebo. Participants of the study were randomised to receive two to four years of either Aspirin or a Placebo. All the Participants were monitored for ten to twenty years of medical. Of the Aspirin engaging persons affected 40 of colon cancer, while 58 of the Placebo take developed human colorectal cancer.
Advantages and disadvantages of Aspirin
The results were statistically interpreted in such a way that Aspirin reduces the risk by about 50 percent, wherein the protective effect lasted for between ten and twenty years after taking the drug. High doses of Aspirin can cause bleeding and stomach ulcers, which is why the research group is currently conducting a further study with three different doses of Aspirin (100, 300 and 600 mg daily) in order to minimize the risk, and still have a protective effect against colorectal cancer. (as)